Correlation between nicotine dependence and inflammatory biomarkers in Thai smokers: Eight weeks of synbiotic intervention

نویسندگان

چکیده

<span>Cigarette smoke contains thousands of man-made substances, and many may contribute to addiction inflammation. This study examined the effect synbiotics on Fagerstrom test for nicotine dependence (FTND) inflammatory markers in Thai smokers. 14 smokers with a Nicotine Dependence Test scores 4 or higher no pregnancy lactation history participated this study. We gave them surveys about FTND continued blood tests Lipopolysaccharide (LPS), lactulose mannitol ratios (LMR), Quinolinic acid (QA), 5-hydroindoleacetic (5-HIAA) record marker levels leaky gut information. Pearson's R-values LPS LMR were 0.444 -0.465. showed positive correlation negative gut, but both relationships weak due gut. The R<sup>2</sup> coefficient was 0.197, p = 0.112, 0.217, </span><em><span>p</span></em><span> 0.001. FTND, LMR, QA significantly reduced, while 5-HIAA elevated. Further investigation is needed determine association between smoking In conclusion, improved permeability, </span>

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ژورنال

عنوان ژورنال: IAES International Journal of Artificial Intelligence

سال: 2022

ISSN: ['2089-4872', '2252-8938']

DOI: https://doi.org/10.11591/ijai.v11.i4.pp1414-1425